What is a migraine?
A migraine is a neurological disorder and for sufferers this can be debilitating and causes nausea,
headache, pain and sensitivity to sound or lights.
What is a Vyepti Infusion?
The newest preventative intravenous (IV) treatment approved 1st August 2023, designed specifically for migraine is called Vyepti which contains the active ingredient eptinezumab. Vyepti is available via the Pharmaceutical Benefits Scheme (PBS) if you fulfill the eligibility criteria.
Vyepti is comprised of antibodies that prevent the activity of calcitonin-gene-related peptide (CRGP). Vyepti works by blocking the activity of CRGP which is associated with a migraine.
What are the benefits?
Vyepti may not be right for everyone as one person may find this extremely effective whilst someone else may not notice much improvement in migraine symptoms.
As the medication is administered via IV into your vein this has rapid absorption into your bloodstream meaning it can start to take effect faster. The Vyepti migraine infusion is only required every 3 months. Booking consistent appointments helps keep regular dosing.
Are there any side effects?
As with any medication Vyepti may cause side effects. The most common of these include a runny nose, cough, sore throat or allergy-related symptoms including hives, rash and itching. The onset of side effects can be delayed and occur at any point up to one week post infusion treatment. If this is the case, consult usual doctor as soon as possible.
Anaphylaxis is a risk and can occur at the commencement of the infusion. At Shire Doctors and Dentists, our medical team are prepared and equipped in the event this may occur.
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How to prepare for your Infusion
Please bring your referral with you or have your specialist send it to us at Shire Doctors and Dentists prior to your infusion. Your doctor may provide you with a prescription along with any specific instructions, alternatively this can be provided on the day during the consultation with one of our GP’s. Have your current Medicare card, recent pathology results and a list of all your current medications to show on the day of your infusion.
There is no need to fast for the infusion, please take your regular medications, eat your breakfast, or lunch, and keep well hydrated prior to the infusion. Wear comfortable clothing, have a drink bottle available and you can choose to lie on the treatment bed or remain in a chair.
What happens during a Vyepti infusion?
A full set of baseline observations and measurements will be taken by Shire Doctors and Dentists nursing staff. An intravenous cannula will be inserted into a vein in your arm. The needle will be removed, leaving a plastic cannula in your vein during the infusion.
The plastic cannula is attached to a long tube, which is connected to the IV Vyepti solution. This solution will be slowly administered into your vein and you will be observed throughout the duration of the infusion.
How long does the infusion take?
The infusion will run for 30 minutes and you will be required to wait for an observation period after completion of the infusion prior to discharge.
We recommend that you arrange someone to drive you home.
Migraine Infusion
To book your appointment for our Migraine infusion clinic, please call 02 9063 8650
Fee (excluding consumable): $170